Non-invasive brain stimulation for Parkinson’s disease: Clinical evidence, latest concepts and future goals: A systematic review

J, Madrid; H, Benninger D.

Abstract:

Parkinson’s disease (PD) is becoming a major public-health issue in an aging population. Available approaches to treat advanced PD still have limitations; new therapies are needed. The non-invasive brain stimulation (NIBS) may offer a complementary approach to treat advanced PD by personalized stimulation. Although NIBS is not as effective as the gold-standard levodopa, recent randomized controlled trials show promising outcomes in the treatment of PD symptoms. Nevertheless, only a few NIBS-stimulation paradigms have shown to improve PD’s symptoms. Current clinical recommendations based on the level of evidence are reported in Table 1 through Table 3. Furthermore, novel technological advances hold promise and may soon enable the non-invasive stimulation of deeper brain structures for longer periods.

Patologie/Applicazioni:

• Stimolazione Magnetica Transcranica (TMS)
• Parkinson
• Stimolazione elettrica transcranica (TES)

Anno:

2021

Tipo di pubblicazione:

Articolo

Parola chiave:

NIBS; stimolazione elettrica transcranica; stimolazione magnetica transcranica; Parkinson; tDCS; tACS

Testata scientifica:

Elsevier

Nota:

In questo articolo vengono spiegati e illustrati i concetti della stimolazione cerebrale non invasiva (NIBS) applicata al morbo di Parkinson effettuando una revisione sistematica della letteratura scientifica presente. La NIBS può migliorare i sintomi causati da questa malattia come sintomi motori, depressione e discinesia. Inoltre, i nuovi progressi tecnologici sono promettenti e potrebbero presto consentire la stimolazione non invasiva delle strutture cerebrali più profonde per periodi più lunghi portando a nuovi risultati.

DOI:

https://doi.org/10.1016/j.jneumeth.2020.108957